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Xunmin OU, Xu ZHANG, Qian ZHANG, Xiliang ZHANG
《能源前沿(英文)》 2013年 第7卷 第3期 页码 263-270 doi: 10.1007/s11708-013-0263-9
关键词: life-cycle analysis (LCA) gas-to-liquid (GTL) LanzaTech process
《化学科学与工程前沿(英文)》 2022年 第16卷 第12期 页码 1700-1712 doi: 10.1007/s11705-022-2207-6
关键词: naphtha catalytic pyrolysis reaction pathway equilibrium yield
“碳达峰、 碳中和战略及路径”项目组
《工程(英文)》 2021年 第7卷 第12期 页码 1673-1677 doi: 10.1016/j.eng.2021.10.003
《环境科学与工程前沿(英文)》 2023年 第17卷 第3期 doi: 10.1007/s11783-023-1637-9
● Converting xylose to caproate under a low temperature of 20 °C by MCF was verified.
关键词: Xylose fermentation Caproate Low temperature Bifidobacterium FAB pathway RBO pathway
Seasonal variations of transport pathways andpotential sources of PM
Yuan Chen, Shaodong Xie, Bin Luo
《环境科学与工程前沿(英文)》 2018年 第12卷 第1期 doi: 10.1007/s11783-018-1009-z
关键词: Transport pathway Backwardtrajectory Clustering analysis Potential source Chengdu
《医学前沿(英文)》 2023年 第17卷 第4期 页码 714-728 doi: 10.1007/s11684-022-0959-5
关键词: FRMD6 lung cancer mTOR pathway
Exploring the methodology and application of clinical pathway in evidence-based Chinese medicine
Sicheng Wang, He Yu, Jianping Liu, Baoyan Liu
《医学前沿(英文)》 2011年 第5卷 第2期 页码 157-162 doi: 10.1007/s11684-011-0128-8
关键词: evidence-based medicine clinical pathway methodology concept technical difficulty
《能源前沿(英文)》 2022年 第16卷 第2期 页码 263-276 doi: 10.1007/s11708-021-0791-7
关键词: ammonia mixed with syngas laminar flame speed kinetic model sensitivity analysis pathway analysis
null
《医学前沿(英文)》 2017年 第11卷 第3期 页码 403-409 doi: 10.1007/s11684-017-0522-y
Tissue factor pathway inhibitor (TFPI) is the main inhibitor of tissue factor-mediated coagulation. TFPI is expressed by endothelial and smooth muscle cells in the vasculature. Endothelium-derived TFPI has been reported to play a regulatory role in arterial thrombosis. However, the role of endogenous TFPI in vascular smooth muscle cells (VSMCs) in thrombosis and vascular disease development has yet to be elucidated. In this TFPIFlox mice crossbred with Sma–Cre mice were utilized to establish TFPI conditional knockout mice and to examine the effects of VSMC-directed TFPI deletion on development, hemostasis, and thrombosis. The mice with deleted TFPI in VSMCs (TFPISma) reproduced viable offspring. Plasma TFPI concentration was reduced 7.2% in the TFPISma mice compared with TFPIFlox littermate controls. Plasma TFPI concentration was also detected in the TFPITie2 (mice deleted TFPI in endothelial cells and cells of hematopoietic origin) mice. Plasma TFPI concentration of the TFPITie2 mice was 80.4% lower (P<0.001) than that of the TFPIFlox mice. No difference in hemostatic measures (PT, APTT, and tail bleeding) was observed between TFPISma and TFPIFlox mice. However, TFPISma mice had increased ferric chloride–induced arterial thrombosis compared with TFPIFlox littermate controls. Taken together, these data indicated that endogenous TFPI from VSMCs inhibited ferric chloride–induced arterial thrombosis without causing hemostatic effects.
关键词: arterial thrombosis conditional knockout mice tissue factor pathway inhibitor vascular smooth muscle cells
《医学前沿(英文)》 2022年 第16卷 第4期 页码 637-650 doi: 10.1007/s11684-021-0864-3
关键词: apigenin aminoglycosides ototoxicity oxidative stress Nrf2 signaling pathway
Biosynthetic pathway of terpenoid indole alkaloids in Catharanthus roseus
null
《医学前沿(英文)》 2014年 第8卷 第3期 页码 285-293 doi: 10.1007/s11684-014-0350-2
Catharanthus roseus is one of the most extensively investigated medicinal plants, which can produce more than 130 alkaloids, including the powerful antitumor drugs vinblastine and vincristine. Here we review the recent advances in the biosynthetic pathway of terpenoid indole alkaloids (TIAs) in C. roseus, and the identification and characterization of the corresponding enzymes involved in this pathway. Strictosidine is the central intermediate in the biosynthesis of different TIAs, which is formed by the condensation of secologanin and tryptamine. Secologanin is derived from terpenoid (isoprenoid) biosynthetic pathway, while tryptamine is derived from indole biosynthetic pathway. Then various specific end products are produced by different routes during downstream process. Although many genes and corresponding enzymes have been characterized in this pathway, our knowledge on the whole TIA biosynthetic pathway still remains largely unknown up to date. Full elucidation of TIA biosynthetic pathway is an important prerequisite to understand the regulation of the TIA biosynthesis in the medicinal plant and to produce valuable TIAs by synthetic biological technology.
关键词: Catharanthus roseus terpenoidindole alkaloids biosynthetic pathway vinblastine vincristine
Genetic evidence in planar cell polarity signaling pathway in human neural tube defects
null
《医学前沿(英文)》 2014年 第8卷 第1期 页码 68-78 doi: 10.1007/s11684-014-0308-4
Neural tube defects (NTDs) are a group of birth anomalies having a profound physical, emotional, and financial effects on families and communities. Their etiology is complex, involving environmental and genetic factors that interact to modulate the incidence and severity of the developing phenotype. The planar cell polarity (PCP) pathway controls the process of convergent extension (CE) during gastrulation and neural tube closure and has been implicated in the pathogenesis of NTDs in animal models and human cohorts. This review summarizes the cumulative results of recent studies on PCP signaling pathway and human NTDs. These results demonstrate that PCP gene alterations contribute to the etiology of human NTDs.
关键词: planar cell polarity neural tube defects rare mutations
Mengjie LI, Chunbao LI, Shangxin SONG, Xinglian XU, Guanghong ZHOU
《农业科学与工程前沿(英文)》 2018年 第5卷 第3期 页码 362-372 doi: 10.15302/J-FASE-2018206
This study compared proteome profiles and morphological changes of rat jejunum in response to different dietary proteins. Fifty male Sprague-Dawley rats were fed with casein (control), and isolated beef, pork, fish and chicken proteins for 14 days. Proteome analysis, histological observation and PEPT1 quantification of the jejunum were performed. The results indicated that rats fed with chicken proteins had higher PEPT1 mRNA and protein levels (P<0.05) but lower villus height and ratio of villus height to crypt depth (V/C ratio, P<0.05) than those fed with casein and pork protein. Label-free LC-MS/MS indicated that, as compared to casein, intake of chicken protein can regulate oligopeptide transport mainly by upregulating PEPT1 protein expression and reducing dipeptidyl-peptidase activity related to biological oxidation, and can reduce oligopeptide absorption capacity by regulating Hippo signaling pathway. Although intake of beef and fish proteins had no significant effect on PEPT1 expression, they altered several signaling pathways.
关键词: Hippo signaling pathway meat protein PEPT1 proteome analysis rat jejunum
NETO2 promotes melanoma progression via activation of the Ca/CaMKII signaling pathway
《医学前沿(英文)》 2023年 第17卷 第2期 页码 263-274 doi: 10.1007/s11684-022-0935-0
关键词: melanoma neuropilin and tolloid-like 2 Ca2+/CaMKII signaling pathway
Zhenfeng Han, Ying Miao, Jing Dong, Zhiqiang Shen, Yuexi Zhou, Shan Liu, Chunping Yang
《环境科学与工程前沿(英文)》 2019年 第13卷 第4期 doi: 10.1007/s11783-019-1133-4
Anaerobically digested swine wastewater was treated by a novel constructed wetland. Tidal operation was better for total nitrogen removal than intermittent flow. Mechanism of nitrogen removal by biozeolite-based constructed wetland was discussed. Simultaneous nitrification and denitrification were determined in zeolite layer.
关键词: Constructed wetland Decentralized swine wastewater Biozeolite Simultaneous nitrification and denitrification Nitrogen removal pathway
标题 作者 时间 类型 操作
Life-cycle analysis of energy use and greenhouse gas emissions of gas-to-liquid fuel pathway from steel
Xunmin OU, Xu ZHANG, Qian ZHANG, Xiliang ZHANG
期刊论文
Thermodynamic analysis of reaction pathways and equilibrium yields for catalytic pyrolysis of naphtha
期刊论文
Low-temperature caproate production, microbial diversity, and metabolic pathway in xylose anaerobic fermentation
期刊论文
Seasonal variations of transport pathways andpotential sources of PM
Yuan Chen, Shaodong Xie, Bin Luo
期刊论文
FERM domain-containing protein FRMD6 activates the mTOR signaling pathway and promotes lung cancer progression
期刊论文
Exploring the methodology and application of clinical pathway in evidence-based Chinese medicine
Sicheng Wang, He Yu, Jianping Liu, Baoyan Liu
期刊论文
Experimental and kinetic study on laminar flame speeds of ammonia/syngas/air at a high temperature and elevated pressure
期刊论文
Endogenous tissue factor pathway inhibitor in vascular smooth muscle cells inhibits arterial thrombosis
null
期刊论文
Apigenin alleviates neomycin-induced oxidative damage via the Nrf2 signaling pathway in cochlear hair
期刊论文
Proteome comparisons reveal influence of different dietary proteins on the development of rat jejunum
Mengjie LI, Chunbao LI, Shangxin SONG, Xinglian XU, Guanghong ZHOU
期刊论文